Familial vs sporadic rheumatoid arthritis (RA). A prospective study in an early RA inception cohort

Catecholestrogens in Rheumatoid Arthritis (RA): Hidden Role

Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme

OBJECTIVE Patients with rheumatoid arthritis (RA) have an increased risk of serious infections. Comparing infection rates across RA populations is complicated by differences in background infection risk, population composition and study methodology. We measured infection rates from five RA registries globally, with the aim to contextualise infection rates from an RA clinical trials population. ...

[Genetics and genomics in rheumatoid arthritis (RA): An update].

Rheumatoid arthritis is a chronic inflammatory autoimmune disease that affects approximately 0.5-1% of the general population and leads to chronic synovial inflammation, destruction of cartilage and bone, and disability. The heritability of rheumatoid arthritis has been estimated to be about 60%, while the contribution of HLA to heritability has been estimated to be 11-37%. Other genes, such as...

Distinct psychological distress trajectories in RA: findings from an inception cohort Short title: Psychological distress trajectories in RA

Objective: As with other chronic physical illness, rates of depressive disorder are high in rheumatoid arthritis (RA). The aim of the current study was to identify distinct trajectories of psychological distress over 10-years in a cohort of RA patients recruited very early in the course of the disease. Methods: Psychological distress as measured by the Hospital Anxiety and Depression Scale tota...

Predictors of Change in Bodily Pain in Early Rheumatoid Arthritis: An Inception Cohort Study

OBJECTIVE To investigate possible predictors for lack of pain improvement after 1 year of treatment for early rheumatoid arthritis (RA). METHODS The Early Rheumatoid Arthritis Network (ERAN) database was used for analysis of baseline and 1-year pain data. The ERAN is a hospital-based inception cohort of 1,189 people. Short Form 36 questionnaire bodily pain scores were used to calculate change...